In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...

Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.

DNA has been proposed as an alternative to magnetic and solid-state devices for storing digital data. In DNA data storage, writing data is performed through DNA synthesis, and reading is done via ...

DNA methylation is a critical epigenetic mechanism in numerous biological processes, including gene regulation, development, ageing and the onset of various diseases such as cancer. Studies of ...

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) have developed a new machine learning method called SAVANA that significantly reduces sequencing errors for cancer genomes. Long-read ...

Scaffolded DNA and RNA origami is a technique that allows scientists to build tiny, highly precise two- and three-dimensional ...

A breakthrough by researchers at Peter Mac will allow scientists to detect, analyze and profile cancer tumors in patients via a simple blood test. The Dawson lab at Peter Mac has developed a method ...

Researchers have developed BayesCNA, a new method that detects cancer DNA at just 5% in blood samples, potentially improving ...