In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

With fresh focus on New Approach Methodologies (NAMs) to move away from animal models in biosciences and preclinical ...

Millions of people around the world are affected by retinal degenerative diseases. In most cases, loss of vision is caused by damage to the macula, a region in the center of the retina. The macula is ...

Researchers in Japan have developed a form of stem cell therapy that "reverses" paralysis. Though the treatment has only seen a 50% success rate so far, two of the four people who received it have ...

A man who was fully paralyzed is now able to stand after receiving an injection of reprogrammed stem cells into his injured spinal cord. The result, announced by researchers in Japan, marks a rare and ...

Mineral casts of cancer cell surfaces reprogram fat cells into stem cells and improve insulin sensitivity in obese mice through purely mechanical cues. (Nanowerk Spotlight) Cancer cells corrupt their ...

Parvalbumin (PV) interneurons act as the brain’s rhythm keepers. By regulating local circuit activity and maintaining excitation–inhibition balance, they help stabilize cortical network function. When ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

Aside from reprogramming and transdifferentiation, the longer-existing approach to generating neurons and NSCs has been differentiating them from pluripotent cells, initially from embryonic stem cells ...