The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

Spatial transcriptomics includes a range of technologies, from sequencing-based platforms such as Visium, Slide-seq, and HDST to imaging-based methods including MERFISH, seqFISH+, and CosMx. Each ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

Spatial analyses uncovered how different tumor regions interact with immune cells and respond to therapies, offering a new ...