Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before. Earlier this week, Life Biosciences, a biotech company focused on reversing age-related ...

Plus: SpaceX has officially delivered the largest IPO in history. This is today's edition of The Download, our weekday newsletter that provides a daily dose of what's going on in the world of ...

A new study by researchers at Fox Chase Cancer Center focusing on pancreatic cancer has shown that a new scoring system can provide a single numerical value that reflects whether the tumor ...

Reprogramming glial cells into neurons holds great promise for regenerative therapies in the central nervous system, but the molecular barriers limiting this process remain largely unknown. This study ...

Direct cardiac reprogramming represents a promising strategy to regenerate damaged myocardium by converting cardiac fibroblasts into induced cardiomyocytes (iCMs). Transient delivery of a ...

Gastric cancer (GC) remains a leading cause of cancer mortality, largely owing to metastasis driven by a highly dynamic tumor microenvironment (TME). Immunosuppressive regulatory T cells (Tregs) and ...

Summary: Researchers have demonstrated that memory decline and symptoms of Alzheimer’s may not be irreversible. By using “partial reprogramming” on specific groups of neurons called engrams—the cells ...

State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry ...

Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart disease. However, current reprogramming strategies require excessive factors due to ...